| |
The need for novel antibiotics is greater now than perhaps any time since the pre-antibiotic era. Indeed, the recent collapse of many pharmaceutical antibacterial groups, combined with the emergence of hypervirulent and pan-antibiotic-resistant bacteria has severely...
Editeur :
Wiley-Blackwell
Parution :
2013-01-14
Collection :
Life Science Research Fundamentals
ePub
|
Treating protein-protein interactions as a novel and highly promising class of drug targets, this volume introduces the underlying strategies step by step, from the biology of PPIs to biophysical and computational methods for their investigation. The main part of the...
Editeur :
Wiley-VCH
Parution :
2013-01-02
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
|
Sets forth the state of the science and technology in plasma protein production With contributions from an international team of eighty leading experts and pioneers in the field, Production of Plasma Proteins for Therapeutic Use presents a comprehensive overview of the...
Editeur :
Wiley
Parution :
2012-12-06
PDF, ePub
|
Filling an obvious gap in the scientific literature, this practice-oriented reference is the first to tie together the working knowledge of large screening centers in the pharmaceutical and biotechnological field. It spans the entire fi eld of this emerging discipline,...
Editeur :
Wiley-VCH
Parution :
2012-12-05
PDF, ePub
|
This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug target-based, rather than the traditional organ/system based, approach this innovative guide reflects the current advances...
Editeur :
Wiley
Parution :
2012-11-30
PDF, ePub
|
Most drugs are analogue drugs. There are no general rules how a new drug can be discovered, nevertheless, there are some observations which help to find a new drug, and also an individual story of a drug discovery can initiate and help new discoveries. Volume III is a...
Editeur :
Wiley-VCH
Parution :
2012-10-15
PDF, ePub
|
In this new edition of a bestseller, all the contents have been brought upto-date by addressing current standards and best practices in the assessment and prediction of ADMET properties. Although the previous chapter layout has been retained, substantial revisions have...
Editeur :
Wiley-VCH
Parution :
2012-09-13
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
|
Closing a gap in the scientifi c literature, this first comprehensive introduction to the topic is based on current best practice in one of the largest pharmaceutical companies worldwide. The first chapters trace the development of our understanding of drug metabolite...
Editeur :
Wiley-VCH
Parution :
2012-09-04
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
|
A comprehensive introduction to using modeling and simulation programs in drug discovery and development Biopharmaceutical modeling has become integral to the design and development of new drugs. Influencing key aspects of the development process, including drug...
Editeur :
Wiley
Parution :
2012-07-31
PDF, ePub
|
Pharmacovigilance Medical Writing covers the preparation of pharmacovigilance documents for all stages of the drug development process (i.e. from clinical development through to applications for marketing authorisations to the post-marketing stage). For each document,...
Editeur :
Wiley-Blackwell
Parution :
2012-06-22
PDF, ePub
|
Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical...
Editeur :
Wiley-VCH
Parution :
2012-06-18
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
|
New and emerging directions in pharmaceutical research to better treat schizophrenia Although the dopamine hypothesis has been the cornerstone of schizophrenia therapeutics, it is clear that dopamine-based approaches do not treat all aspects of the disease. Moreover,...
Editeur :
Wiley
Parution :
2012-06-06
PDF, ePub
|
Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for development. The first part provides a basic understanding of the factors governing protein-ligand interactions, followed by a...
Editeur :
Wiley-VCH
Parution :
2012-06-04
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
|
The opportunities and challenges of using dendrimers to improve drug delivery Among pharmaceutical and biomedical researchers, the use of dendrimers in drug delivery systems has attracted increasing interest. In particular, researchers have noted that the volume of a...
Editeur :
Wiley
Parution :
2012-05-23
Collection :
Wiley Series in Drug Discovery and Development
PDF, ePub
|
Cost-effective manufacturing of biopharmaceutical products is rapidly gaining in importance, while healthcare systems across the globe are looking to contain costs and improve efficiency. To adapt to these changes, industries need to review and streamline their...
Editeur :
Wiley-VCH
Parution :
2012-05-14
PDF, ePub
|
The Latest Applications For Cellmechanism Research in Drug Discovery Designed to connect research on cell mechanisms with the drug discovery process, Therapeutic Targets: Modulation, Inhibition, and Activation introduces readers to a range of new concepts and novel...
Editeur :
Wiley
Parution :
2012-04-20
PDF, ePub
|
Learn why some drug discovery and development efforts succeed . . . and others fail Written by international experts in drug discovery and development, this book sets forth carefully researched and analyzed case studies of both successful and failed drug discovery and...
Editeur :
Wiley
Parution :
2012-04-19
PDF, ePub
|
A comprehensive guide to optimizing the lifecycle management of pharmaceutical brands The mounting challenges posed by cost containment policies and the prevalence of generic alternatives make optimizing the lifecycle management (LCM) of brand drugs essential for...
Editeur :
Wiley
Parution :
2012-04-16
PDF, ePub
|
The how's and why's of successful drug repositioning Drug repositioning, also known as drug reprofiling or repurposing, has become an increasingly important part of the drug development process. This book examines the business, technical, scientific, and operational...
Editeur :
Wiley
Parution :
2012-04-11
PDF, ePub
|
Explains how to perform and analyze the results of the latest physicochemical methods With this book as their guide, readers have access to all the current information needed to thoroughly investigate and accurately determine a compound's pharmaceutical properties and...
Editeur :
Wiley
Parution :
2012-04-11
PDF, ePub
|